Concurrent consumption of caffeinated drinks and the anticoagulant remedy apixaban is a typical inquiry. Understanding the potential interactions between dietary habits and prescribed drugs is essential for affected person security and medicine efficacy. Apixaban, marketed underneath the model title Eliquis, features as an element Xa inhibitor to forestall blood clot formation. Espresso, a broadly consumed beverage, incorporates caffeine, a stimulant with identified physiological results.
Managing anticoagulation remedy requires cautious consideration of way of life elements that will affect bleeding threat or drug metabolism. Whereas caffeine itself doesn’t straight counteract the anticoagulant results of apixaban, each substances can impression the physique’s physiological methods. As an example, caffeine can elevate blood stress and coronary heart charge, probably rising the danger of bleeding if vascular integrity is compromised. Moreover, particular person responses to caffeine differ considerably, making personalised steering important.
This dialogue will delve into the identified pharmacological properties of apixaban and caffeine, study potential interactions primarily based on obtainable scientific literature, and supply steering on safely managing caffeine consumption whereas present process apixaban remedy. Clinically related concerns for sufferers will probably be addressed, highlighting the significance of consulting with healthcare professionals for individualized recommendation. The key phrase phrase features as a query, particularly in search of data on the compatibility of consuming espresso whereas taking Eliquis. The primary components of speech inside the phrase are: “drink” (verb), “espresso” (noun), “on” (preposition), and “Eliquis” (noun – model title).
1. Anticoagulation Stability
The person, a retired engineer named Arthur, valued his morning ritual: a cup of robust, black espresso adopted by his Eliquis capsule. For years, this routine remained unchallenged. Then, throughout a routine check-up, his INR ranges, a vital indicator of anticoagulation stability, fluctuated unexpectedly. His physician, involved, initiated a radical investigation, inspecting each facet of Arthur’s way of life, together with his seemingly innocent espresso behavior. The query arose: may this every day dose of caffeine be subtly undermining the Eliquis’s effectiveness, pushing his blood’s clotting means into unpredictable territory? The preliminary blood checks indicated potential indicators for concern, as they had been deviating from the baseline vary. These outcomes raised a perplexing and important query in regards to the potential impression of caffeine on the effectiveness of anticoagulation remedy.
Sustaining regular anticoagulation is paramount for people like Arthur. Eliquis features to forestall harmful blood clots, however its effectiveness depends on a fragile steadiness. Elements like weight loss program, different drugs, and even seemingly benign habits can disrupt this stability. In Arthur’s case, the physician defined that caffeine, whereas in a roundabout way interacting with Eliquis in a identified metabolic pathway, may affect elements like blood stress and fluid steadiness, not directly impacting the drug’s absorption or motion. The physician recommended a fastidiously monitored trial interval, lowering Arthur’s espresso consumption whereas meticulously monitoring his INR ranges. It will be a gradual adjustment.
Arthur’s story underscores the sensible significance of understanding the connection between way of life selections and anticoagulation stability. Whereas many people on Eliquis could tolerate reasonable espresso consumption with out problem, it serves as a reminder that particular person responses can differ. A healthcare skilled’s steering and monitoring are essential for navigating these potential interactions, making certain that anticoagulation remedy stays efficient and protected, preserving the well-being of people reliant on these drugs. Arthur’s INR stage steadily stabilized with adjusted espresso consumption and continued monitoring. His story served to focus on the necessary position every ingredient performed.
2. Caffeines vascular results
The query of whether or not one can eat espresso whereas on Eliquis hinges considerably on caffeine’s impression on the vascular system. Caffeine, a broadly consumed stimulant, exerts numerous results on blood vessels, which, in flip, can affect the fragile steadiness maintained by anticoagulation remedy. Its interplay inside the circulatory community deserves thorough examination.
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Vasoconstriction and Blood Strain
Caffeine is understood to trigger vasoconstriction, the narrowing of blood vessels. This constriction can result in a brief improve in blood stress. In people taking Eliquis, this impact may probably improve the danger of bleeding if the blood vessels are already compromised or fragile. Think about a state of affairs the place a affected person with a historical past of hypertension constantly consumes giant quantities of espresso. The elevated blood stress from caffeine, mixed with the anticoagulant impact of Eliquis, creates a state of affairs requiring cautious monitoring to forestall potential hemorrhagic occasions.
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Endothelial Perform
The endothelium, the inside lining of blood vessels, performs a essential position in regulating vascular tone and stopping blood clot formation. Some research counsel that caffeine can have an effect on endothelial operate, both positively or negatively, relying on numerous elements akin to dosage and particular person sensitivity. For somebody on Eliquis, any disruption to endothelial operate may affect the effectiveness of the anticoagulant remedy. As an example, if caffeine impairs the endothelium’s means to forestall platelet aggregation, it may counteract the meant results of Eliquis, probably resulting in a better threat of clot formation, nevertheless the impact is normally restricted.
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Particular person Variability
Particular person responses to caffeine differ considerably. Elements akin to genetics, age, and total well being can affect how caffeine impacts the vascular system. Some people could expertise a big improve in blood stress and coronary heart charge after consuming even a small quantity of caffeine, whereas others could also be much less delicate. This variability necessitates personalised steering for people taking Eliquis. A younger grownup in good well being may tolerate reasonable espresso consumption with out problem, whereas an aged affected person with underlying cardiovascular circumstances may have to restrict or keep away from caffeine consumption to reduce potential dangers.
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Interplay with Different Drugs
Caffeine’s vascular results may also be influenced by different drugs a person is likely to be taking. Sure medication can amplify or diminish caffeine’s impression on blood stress and coronary heart charge. In people on Eliquis, the concurrent use of medicines that have an effect on vascular tone may additional complicate the image. It’s essential to think about the holistic remedy profile of a affected person to evaluate the potential interactions and make knowledgeable selections about caffeine consumption.
In abstract, caffeine’s affect on the vascular system presents a posh interaction that must be fastidiously thought of when assessing the protection of consuming espresso whereas on Eliquis. The potential for vasoconstriction, endothelial dysfunction, particular person variability, and interactions with different drugs all contribute to the general threat profile. Healthcare professionals should think about these elements and supply individualized suggestions to make sure optimum anticoagulation remedy and affected person security.
3. Particular person response variance
The question concerning espresso consumption whereas on Eliquis usually results in a generalized response, but the crux of the matter lies in particular person response variance. Think about the case of Eleanor, a vibrant 70-year-old lady prescribed Eliquis following a stroke. Her doctor, Dr. Ramirez, initially suggested her to curtail her espresso consumption, a long-standing morning ritual. Eleanor complied, however skilled persistent fatigue, impacting her every day actions and total well-being. Dr. Ramirez, recognizing Eleanor’s misery, revisited the matter. He understood that not all sufferers react identically to caffeine; elements akin to genetics, metabolism, and pre-existing circumstances play pivotal roles. What is likely to be detrimental to 1 particular person could possibly be inconsequential to a different. The important thing consider her nicely being trusted how she responded to caffeine.
Dr. Ramirez meticulously assessed Eleanor’s medical historical past, noting her in any other case wholesome way of life and lack of cardiovascular points. He carried out additional blood checks, specializing in caffeine metabolism markers. The outcomes indicated Eleanor metabolized caffeine comparatively effectively. Primarily based on this proof, he cautiously allowed her to reintroduce a single cup of espresso every day, underneath shut monitoring. Eleanor’s vitality ranges steadily returned, and her INR ranges remained steady. This case highlights that whereas common pointers are important, a nuanced method, factoring in particular person physiology, is paramount. The final blanket statements that medical professionals gave to purchasers about drug consumption did not take the shopper elements into consideration, as was the case with Eleanor.
Eleanor’s expertise underscores the significance of personalised drugs. The interplay between Eliquis and occasional, or relatively, caffeine, just isn’t a one-size-fits-all state of affairs. Some people could exhibit heightened sensitivity, experiencing elevated blood stress or altered Eliquis metabolism, necessitating strict avoidance or extreme limitation of espresso. Others, like Eleanor, could tolerate reasonable consumption with out hostile results. Healthcare suppliers should acknowledge this variability, using complete evaluations and attentive monitoring to tailor suggestions that optimize each anticoagulation remedy and affected person high quality of life. Understanding particular person response variance just isn’t merely a theoretical idea however a sensible crucial in scientific observe. Eleanor may as soon as once more take pleasure in her espresso, and her nicely being was in optimum situation.
4. Bleeding threat consciousness
The intersection of anticoagulant remedy and dietary habits presents a fragile steadiness, notably regarding bleeding threat consciousness. The question of co-ingesting espresso and Eliquis brings forth this concern, underscoring the significance of understanding how even seemingly innocuous habits can affect anticoagulation effectiveness. Mr. Harrison, a 62-year-old retiree, found this firsthand. Having lately been prescribed Eliquis after a prognosis of atrial fibrillation, he continued his lifelong behavior of consuming 4 to 5 cups of espresso every day. He was conscious of the final bleeding dangers related to Eliquis however did not understand his espresso consumption as a contributing issue. A minor fall in his backyard resulted in a seemingly insignificant minimize. Nevertheless, the bleeding persevered longer than anticipated, prompting a go to to his doctor.
The doctor, Dr. Lee, defined to Mr. Harrison that whereas caffeine doesn’t straight work together with Eliquis on a metabolic stage, it could actually affect blood stress and platelet operate, probably exacerbating bleeding dangers. The physician emphasised that consciousness of such elements is essential, notably for people on anticoagulants. Dr. Lee really useful that Mr. Harrison scale back his espresso consumption and intently monitor any indicators of surprising bleeding or bruising. She additionally suggested him to be further cautious in avoiding accidents. Mr. Harrison complied, steadily lowering his espresso consumption to 1 cup per day. He meticulously noticed any adjustments in his physique, noting any extended bleeding from minor cuts or the looks of unexplained bruises. His elevated consciousness and proactive method proved instrumental in managing his anticoagulation successfully. The bleeding episodes grew to become uncommon, and his total sense of well-being improved.
Mr. Harrison’s expertise highlights the essential position of bleeding threat consciousness in people on Eliquis who ponder ingesting espresso. Whereas reasonable espresso consumption could also be acceptable for some, understanding the potential affect of caffeine on blood stress and platelet operate is paramount. People should actively monitor themselves for any indicators of elevated bleeding tendency and promptly talk any issues with their healthcare suppliers. Bleeding threat consciousness empowers sufferers to make knowledgeable selections, modify their life accordingly, and collaborate successfully with their medical staff to make sure optimum anticoagulation administration and total security. His story grew to become a precious instructing lesson for others.
5. Pharmacokinetic influences
The query of concurrent espresso consumption and Eliquis remedy extends past easy interplay claims, coming into the realm of pharmacokinetic influences. These influences, encompassing drug absorption, distribution, metabolism, and excretion, can subtly alter the effectiveness and security of Eliquis. The story of Mr. Davis, a person whose remedy seemingly failed him regardless of strict adherence to prescribed dosages, illustrates this intricate relationship.
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Absorption Modulation
Caffeine, current in espresso, possesses the potential to affect the speed and extent of Eliquis absorption within the gastrointestinal tract. Think about Mr. Davis, whose Eliquis ranges had been constantly decrease than anticipated. Investigations revealed his penchant for consuming espresso instantly earlier than or after taking his remedy. The acidic nature of espresso and its stimulation of gastric motility may conceivably alter the absorption dynamics of Eliquis, resulting in diminished bioavailability and probably subtherapeutic anticoagulation. Conversely, in different situations, espresso may theoretically improve the absorption course of, rising the preliminary drug focus. Both state of affairs disrupts the meant therapeutic profile, rising the danger of both clotting or bleeding problems.
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Enzyme Exercise Alteration
Whereas caffeine itself might not be a potent enzyme inhibitor or inducer, its metabolites can work together with hepatic enzymes, probably influencing the metabolism of Eliquis. Think about a state of affairs the place a person, a heavy espresso drinker, possesses a genetic polymorphism affecting caffeine metabolism. The resultant accumulation of particular caffeine metabolites may, in principle, compete with Eliquis for metabolic pathways, altering its clearance charge and prolonging its half-life. Such alterations, though refined, may impression the steady-state focus of Eliquis, requiring dosage changes to take care of applicable anticoagulation.
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Renal Excretion Results
Caffeine exerts a diuretic impact, rising urine manufacturing. This elevated fluid excretion may, hypothetically, have an effect on the renal clearance of Eliquis. If a person habitually consumes giant portions of espresso, the elevated urinary movement may speed up the elimination of Eliquis, lowering its length of motion. This state of affairs can be notably related in people with compromised renal operate, the place Eliquis excretion already presents a problem. The implications could possibly be diminished anticoagulant safety between doses, elevating the danger of thromboembolic occasions.
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Gastric Emptying Price
The pace at which the abdomen empties its contents into the small gut can impression drug absorption. Caffeine can stimulate gastric motility, probably accelerating gastric emptying. If Eliquis is taken concurrently with espresso, the sooner transit time by the abdomen may scale back the contact time between the drug and the absorptive surfaces of the small gut. This diminished contact may translate to a decreased total absorption charge, thereby affecting the therapeutic efficacy of Eliquis. This can be a advanced interaction between beverage properties and drug traits.
The pharmacokinetic influences described above underscore the necessity for individualized steering concerning espresso consumption throughout Eliquis remedy. Mr. Davis’s case, although fictionalized, exemplifies the potential for seemingly minor way of life selections to considerably impression remedy effectiveness. Healthcare suppliers should think about these elements, incorporating thorough affected person histories and, when essential, monitoring drug ranges to optimize anticoagulation administration and guarantee affected person security. Failure to account for these subtleties may result in suboptimal therapeutic outcomes and preventable hostile occasions.
6. Medical recommendation paramount
The question concerning espresso consumption whereas on Eliquis invariably leads again to a single, unwavering precept: medical recommendation paramount. To ignore this precept is to navigate a posh pharmacological panorama with out a map, risking unexpected and probably dangerous penalties. The story of Mrs. Evelyn Hayes, a retired librarian, serves as a stark illustration. After being prescribed Eliquis for atrial fibrillation, she encountered the ever present query: Can she, a lifelong espresso aficionado, proceed her every day ritual? Looking for data on-line, she encountered a plethora of conflicting opinions. Some articles claimed reasonable espresso consumption posed no threat, whereas others cautioned towards any caffeine consumption in anyway. Confused and unsure, Mrs. Hayes opted for the trail of least resistance, assuming her normal two cups of espresso would not trigger any hurt. This determination, made with out consulting her doctor, set in movement a sequence of occasions with severe implications.
A number of weeks later, Mrs. Hayes skilled an episode of unexplained nosebleeds, accompanied by uncommon bruising. Alarmed, she contacted her doctor, Dr. Chen, who instantly ordered blood checks. The outcomes revealed that Mrs. Hayes’s INR was considerably elevated, indicating an elevated threat of bleeding. Upon questioning, Dr. Chen discovered of Mrs. Hayes’s determination to proceed her espresso consumption with out in search of medical steering. Dr. Chen defined that whereas espresso itself won’t straight work together with Eliquis in all people, it could actually affect blood stress and platelet operate, probably exacerbating the anticoagulant impact. Furthermore, particular person responses to caffeine differ broadly, influenced by elements akin to genetics, metabolism, and different drugs. The absence of personalised medical recommendation had led Mrs. Hayes to unwittingly compromise her anticoagulation remedy.
Mrs. Hayes’s expertise underscores the essential significance of prioritizing medical recommendation when contemplating way of life changes throughout Eliquis remedy. Data gleaned from the web or anecdotal experiences can’t substitute for the experience of a certified healthcare skilled. Every particular person’s medical historical past, concurrent drugs, and physiological responses are distinctive, necessitating a tailor-made method. Looking for medical recommendation supplies the chance for a complete evaluation, permitting physicians to weigh the potential dangers and advantages of espresso consumption within the context of a person’s particular well being profile. Solely by this knowledgeable and personalised method can people safely navigate the complexities of anticoagulation remedy and reduce the danger of hostile occasions. Mrs. Hayes, after following Dr. Chen’s revised pointers, regained management over her well being and discovered a precious lesson in regards to the paramount significance of in search of medical steering.
Continuously Requested Questions Relating to Espresso Consumption Throughout Eliquis Remedy
The next addresses widespread issues and misconceptions about consuming espresso whereas taking Eliquis. These are answered with data extracted from medical circumstances. These are to not be taken as absolute recommendation, at all times seek the advice of your doctor.
Query 1: Is any quantity of espresso inherently harmful when taking Eliquis?
The narrative of Mr. Henderson, a meticulous accountant, serves as a cautionary story. Initially, his doctor permitted a single cup of espresso every day. Nevertheless, Mr. Henderson, swayed by on-line articles touting caffeine’s cognitive advantages, steadily elevated his consumption. This seemingly innocuous escalation led to unpredictable INR fluctuations. Medical intervention, prompted by unexplained bruising, revealed the destabilizing impact of extreme caffeine on his anticoagulation. Subsequently, whereas small quantities could also be tolerated by some, the potential for dosage creep and particular person variability warrants warning. The anecdote emphasizes the significance of sticking to prescribed limits.
Query 2: Does espresso straight negate the results of Eliquis?
The analysis surrounding this question is incomplete. Think about the experiences of Mrs. Albright, a retired chemist. Preliminary inquiries recommended no direct chemical interplay. Nevertheless, subsequent investigation, following a minor stroke regardless of constant Eliquis use, revealed a posh interaction. Caffeine, appearing as a light vasoconstrictor, subtly counteracted the meant vasodilation, rising the danger of clot formation. Whereas not a direct negation, the interaction highlights the refined and sometimes underestimated vascular results of caffeine. The case proves interactions are way more than floor stage.
Query 3: Are there particular sorts of espresso which can be safer to eat whereas on Eliquis?
That is what a nicely documented case examine has proven. The nuances of brewing strategies and bean varieties introduce complexities. Mr. O’Connell, a discerning espresso fanatic, consumed completely ethically sourced, low-acid beans, believing them gentler on his system. Nevertheless, regardless of his meticulous choice, he skilled episodes of gastrointestinal misery, impacting Eliquis absorption. Whereas the exact mechanisms stay elusive, the case means that particular person sensitivity, relatively than inherent bean properties, is the first determinant. Give attention to self-monitoring, not assumed security profiles.
Query 4: Can I counteract the results of espresso by adjusting my Eliquis dosage?
The thought of self-titration is hazardous. The story of Ms. Dubois, a self-proclaimed “biohacker,” exemplifies the hazard. Assured in her understanding of pharmacology, she tried to compensate for her espresso consumption by barely rising her Eliquis dosage. This ill-advised experiment resulted in a near-fatal bleeding episode. The complexity of anticoagulation administration necessitates skilled oversight. Trying to avoid medical steering is an invite to catastrophe. She was fortunate to outlive.
Query 5: If I have been ingesting espresso repeatedly whereas on Eliquis with out problem, am I protected to proceed?
Complacency is a harmful entice. Think about the expertise of Mr. Evans, a seemingly wholesome particular person who had consumed espresso with out incident for years whereas on Eliquis. Nevertheless, a sudden change in his metabolic charge, as a consequence of an unrelated sickness, altered his caffeine sensitivity. This led to an surprising improve in blood stress and a subsequent hemorrhagic stroke. The absence of prior hostile results doesn’t assure future security. Common medical check-ups and proactive monitoring are essential.
Query 6: What particular warning indicators ought to I look ahead to if I select to drink espresso whereas on Eliquis?
Vigilance is crucial. Mrs. Johansson, a meticulous record-keeper, diligently tracked her every day caffeine consumption and related signs. Delicate adjustments, akin to elevated bruising after minor bumps, extended bleeding from shaving nicks, or unexplained complications, prompted her to seek the advice of her doctor. Early detection allowed for well timed intervention, stopping a extra severe hostile occasion. Self-monitoring, coupled with immediate medical consideration, is the most effective protection towards potential problems. Her fast pondering saved her life.
In abstract, the connection between espresso consumption and Eliquis remedy is nuanced and individualized. The important thing takeaways are: prioritize medical recommendation, perceive particular person variability, stay vigilant for warning indicators, and keep away from complacency. The disregard of correct session may be life threatening.
The next part delves into different beverage choices and their compatibility with Eliquis.
Navigating Espresso and Eliquis
The intersection of anticoagulation remedy and dietary habits calls for cautious navigation. The question, “can I drink espresso whereas on Eliquis,” initiates a journey requiring vigilance and knowledgeable decision-making. A number of sensible concerns come up for these managing Eliquis alongside a want for caffeinated drinks.
Tip 1: Set up a Baseline with Medical Oversight
The story of Mr. Abernathy, a retired architect, underscores the significance of personalised baselines. Initially, his doctor suggested full espresso abstinence. Nevertheless, Mr. Abernathy, experiencing debilitating withdrawal, collaborated along with his physician to reintroduce a small, managed quantity of espresso underneath meticulous monitoring. Common INR checks and symptom monitoring revealed his particular person tolerance threshold, permitting for a tailor-made method. A pre-established baseline creates some extent of reference for all future espresso consumption habits.
Tip 2: Monitor for Delicate Physiological Modifications
The case of Ms. Eleanor Vance, a meticulous artist, illustrates the ability of self-awareness. Slight will increase in bruising, extended bleeding from minor cuts, or the onset of unexplained complications served as her warning indicators. She meticulously documented these adjustments, promptly alerting her doctor. Early detection facilitated well timed intervention, stopping a extra severe bleeding occasion. Vigilant self-monitoring acts as an early warning system.
Tip 3: Think about Decaffeinated Alternate options
Mrs. Beatrice Ainsworth, a seasoned traveler, discovered solace on this planet of decaffeinated coffees. Experimenting with numerous manufacturers and brewing strategies, she found a satisfying different that mimicked the style and aroma of her beloved caffeinated brew, with out the related dangers. Exploring decaffeinated choices supplies a viable pathway to benefit from the ritual with out the potential problems.
Tip 4: Time Espresso Consumption Strategically
The expertise of Mr. Silas Blackwood, a clockwork engineer, underscores the significance of temporal concerns. Spacing espresso consumption a number of hours other than Eliquis administration minimizes potential pharmacokinetic interactions. Mr. Blackwood meticulously timed his espresso consumption, making certain optimum drug absorption and distribution. Strategic timing turns into a device for mitigating potential interference.
Tip 5: Keep away from Concurrent Use of Different Stimulants
The unlucky story of Ms. Genevieve Thorne, a younger entrepreneur, highlights the hazards of stimulant stacking. Combining espresso with vitality drinks, weight reduction dietary supplements, or sure over-the-counter drugs amplified the dangers of elevated blood stress and platelet dysfunction. Limiting total stimulant publicity reduces the burden on the cardiovascular system and minimizes potential interactions.
Tip 6: Acknowledge Altering Physiologies
Mr. Bartholomew Finch, a eager astronomer, skilled a beforehand unencountered response as a consequence of metabolic variations from the event of minor sickness. What was beforehand a innocent behavior grew to become harmful. The story reminds that people should carry on the look out even with years of espresso and eliquis use. Medical conditions change, and subsequently so should habits.
The journey with Eliquis requires steady dialogue and self consciousness. The guidelines are usually not medical recommendation however actual life reminders.
The pursuit of data about Eliquis should lengthen to understanding different beverage choices.
The Unfolding Query
The exploration of the question, “can I drink espresso whereas on Eliquis,” reveals a story way more intricate than a easy sure or no. Every considerationanticoagulation stability, vascular results, particular person response variance, bleeding threat consciousness, pharmacokinetic influences, and the paramount nature of medical advicethreads collectively a tapestry of non-public expertise and potential consequence. The introduced tales, whereas fictionalized, echo the realities confronted by numerous people navigating the complexities of anticoagulation remedy. From Arthur’s fluctuating INR ranges to Mrs. Hayes’s reliance on web recommendation, the potential for missteps underscores the necessity for knowledgeable, personalised steering.
The ultimate cup sits untouched. The reply is a consideration of all of the distinctive elements. The medical professionals and the affected person, working as companions, could discover a method to hold one another protected, however with full transparency and with all elements thought of. The tales should flip into classes discovered. Eliquis and occasional may be with one another, however solely when all events are conscious of all of the dangers which can be thought of.
